Publications

  • Toyomoto, M., Ishido, S., Miyasaka, N., Sugimoto, H., and Kohsaka, H. Anti-arthritic effect of E3 ubiquitin ligase, c-MIR,expression in the joints. International immunology 2011 Mar; 23(3): 177-83.

  • Goto, E., Yamanaka, Y., Ishikawa, A., Aoki-Kawasumi, M., Mito-Yoshida, M., Ohmura-Hoshino, M., Matsuki, Y., Kajikawa, M., Hirano, H., and Ishido, S*. Contribution of K11-linked ubiquitination to MIR2-mediated MHC class I internalization. J Biol Chem. 2010 Nov; 285(46): 35311-9. Epub 2010 Sep 10.

  • Tze, LE., Horikawa, K., Domaschenz, H., Howard, DR., Roots, CM., Rigby, RJ., Way, DA., Ohmura-Hoshino, M., Ishido, S., Andoniou, CE., Degli-Esposti, MA., and Goodnow, CC. CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. J. Exp. Med. 2011 Jan 17;208(1): 149-65. Epub 2011 Jan 10.

  • Walseng, E., Furuta, K., Bosch, B., Weih, KA., Matsuki, Y., Bakke, O., Ishido, S., and Roche, PA. Ubiquitination Regulates MHC Class II-Peptide Complex Retention and Degradation in Dendritic Cells. Proc. Natl. Acad. Sci. U S A. 2010 Nov;107(47):20465-70. Epub 2010 Nov 8

  • Ishido, S*., Matsuki, Y., Goto, E., Kajikawa, M., Ohmura- Hoshino, M. MARCH-I: a new regulator of dendritic cell function. Mol Cells. 2010 Mar;29(3):229-32. Epub 2010 Mar 4.

  • Ohmura-Hoshino, M., Matsuki, Y., Mito-Yoshida, M., Goto,E., Aoki-Kawasumi, M., Nakayama, M., Ohara, O., and Ishido, S*. Cutting edge: Requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cell. J. Immunol. 2009 Dec;183(11):6893-7.

  • Deng, L., Adachi, T., Kitayama, K., Bungyoku, Y., Kitazawa, S. , Ishido, S., Shoji, I. and Hotta, H. Hepatitis C Virus Infection Induces Apoptosis through a Bax-triggered, Mitochondria-mediated, Caspase-3-dependent Pathway. J Virol. 2008 Nov;82(21):10375-85. Epub 2008 Sep 3.

  • Ishido, S*., Goto, E., Matsuki, M. and Ohmura-Hoshino, M: E3 ubiquitin ligases for MHC molecules, Current Opinion in Immunology 2009 Feb;21(1):78-83. Epub 2009 Feb 7.

  • Young, LJ., Wilson, NS., Schnorre, PM., Proietto, A., Broeke, T., Matsuki, Y., Mount, AM., Belz, GT., O'Keeffe, M., Ohmura-Hoshino, M., Ishido, S., Stoorvogel, M., Heath, WR., Shortman, K. and Villadangos, JA. Differential Regulation of MHC class II Synthesis and Turn-over Confers Distinct Antigen Presenting Properties to Conventional and Plasmacytoid Dendritic Cells, Nature Immunology 2008 Nov;9(11):1244-52. Epub 2008 Oct 12.

  • Goto, E. , Mito-Yoshida, M. , Uematsu, M. , Aoki, M. , Matsuki, Y. , Ohmura-Hoshino, M. , Hotta, H. , Miyagishi, M. , Ishido, S. An excellent monitoring system for surface ubiquitination-induced internalization in mammals. PLoS ONE 2008 ; 3 (1) : e1490.

  • Matsuki, Y., Ohmura-Hoshino, M., Goto E., Aoki M., Mito-Yoshida M., Uematsu M., Hasegawa T., Koseki H., Ohara O., Nakayama M., Toyooka K., Matsuoka K., Hotta H., Yamamoto A. and Ishido,S. Novel regulation of MHC class II function in B cells. EMBO J. 2007, Feb.7; 26(3);846-854; Epub. 2007 Jan 25,
  • Ohgimoto K, Ohgimoto S, Ihara T, Mizuta H, Ishido S, Ayata M, Ogura H, Hotta H. Difference in production of infectious wild-type measles and vaccine viruses in monocyte-derived dendritic cells. Virus Res. 2006 (in press)

  • Ohmura-Hoshino M., Goto, E., Matsuki, Y., Aoki, M., Mito, M., Uematsu, M., Hotta, H. and Ishido, S. A novel family of membrane-bound E3 ubiquitin ligases J. Biochem. (Tokyo) 2006 Aug;140(2):147-54.

  • Yonashiro R, Ishido S, Kyo S, Fukuda T, Goto E, Matsuki Y, Ohmura-Hoshino M, Sada K, Hotta H, Yamamura H, Inatome R, Yanagi S. A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics. EMBO J. 2006 Aug 9 ; 25(15):3618-26. Epub 2006 Jul 27.

  • Ohmura-Hoshino, M., Matsuki, Y., Aoki,M., Goto, E., Mito, M., M.Uematsu,, Kakiuchi, T., Hotta H. and Ishido S. Inhibition of MHC class II expression and immune responses by c-MIR1 J. Immunol. 2006 Jul 1;177(1):341-54.

  • Nomura-Takigawa Y, Nagano-Fujii M, Deng L, Kitazawa S, Ishido S, Sada K, Hotta H. Non-structural protein 4A of Hepatitis C virus accumulates on mitochondria and renders the cells prone to undergoing mitochondria-mediated apoptosis.J Gen Virol. 2006 Jul;87(Pt 7):1935-45.

  • 星野真理、後藤栄治、石戸聡 膜結合型新規E3ユビキチンリガーゼファミリー 実験医学 2006 p.167-172

  • 後藤栄治、星野真理、松木洋平、水戸麻理、石戸聡 KSHVに対する免疫応答 日本臨床増刊号 Vol64,(3), 2006;568-575

  • Tanaka M, Nagano-Fujii M, Deng L, Ishido S, Sada K, Hotta H. Single-point mutations of hepatitis C virus NS3 that impair p53 interaction and anti-apoptotic activity of NS3. Biochemical and Biophysical Research Communicaitons:340(3),2006,792-799

  • Taguchi, T., Nagano-Fujii, M., Akutsu,M., Kadoya, H., Ohgimoto, S., Ishido, S. and Hotta, H. Related Articles, Links Hepatitis C virus NS5A protein interacts with 2',5'-oligoadenylate synthetase and inhibits antiviral activity of IFN in an IFN sensitivity-determining region-independent manner.J Gen Virol.,85(Pt 4):959-69, 2004

  • Uchida, D., Hatakeyama, S., Matsushima, A., Han, H., Ishido, S., Hotta, H., Kudoh, J., Shimizu, N., Doucas, V., Nakayama, KI., Kuroda, N. and Matsumoto, M. Related Articles, Links AIRE functions as an E3 ubiquitin ligase. J Exp. Med. 19,199(2):167-72., 2004

  • 石戸聡 ユビキチンとウイルス感染 医学のあゆみ,211(1):108-113, 2004

  • 石戸聡、後藤栄治、松木洋平、佐藤祐也、堀田博. 新たな免疫抑制性E3ユビキチンリガーゼファミリー Molecular medicine, 40:312-320,2004

  • Goto, E., Ishido, S., Sato, Y., Ohgimoto, S., Ohgimoto, K., Nagano-Fujii, M. and Hotta H. c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and 2 and has similar activity. J Biol Chem 278:14657-14668, 2003

  • 石戸聡、後藤栄治、佐藤祐也、堀田博. 免疫抑制性ウイルス蛋白とその機能類似分子群 臨床免疫、39(2):153-160, 2003

  • Means, RE., Ishido, S., Alvarez, X. and Jung, JU. Multiple endocytotic trafficking pathway of MHC class I molecules induced by a Herpesvirus protein. EMBO J., 21 (7):1638-1649, 2002

  • 石戸聡、後藤栄治、佐藤祐也、堀田博.ウイルスによる抗原提示抑制機構 蛋白質核酸酵素、47(16 Suppl): 22145-22151, 2002

  • 石戸聡 KSHVによる免疫回避機構 臨床免疫、37(3):322-327, 2002

  • Means, RE., Choi, JK., Nakamura, H., Chung ,YH., Ishido, S. and Jung, JU. Immune evasion strategies of Kaposi’s sarcoma-associated herpesvirus. Curr. Top. Microbiol. Immunol. 269: 187-201, 2002

  • Rikitake, Y., Kawashima, S., Takahashi, T., Ueyama, T., Ishido, S., Inoue, N., Hirata, K.and Yokoyama, M. Regulation of tyrosine phosphorylation of PYK2 in vascular endothelial cells by lysophosphatidylcholine. Am J Physiol Heart Circ Physiol. 281(1):266-74, 2001

  • Yoshida, I., Oka, K., Hidajat R., Nagano-Fujii, M., Ishido, S and Hotta, H. Inhibition of p21/Waf1/Cip1/ Sdi 1 expression by hepatitis C virus core protein. Microbiol. Immunol., 45(10): 689-697, 2001

  • Ishido, S., Choi, JK., Lee, BS., Wang, C., DeMaria, M., Johnson, RP., Cohen, GB. and Jung, JU. Inhibition of natural killer cell-mediated cytotoxicity by Kaposi's sarcoma-associated herpesvirus K5 protein. Immunity.,13(3):365-374, 2000

  • Choi, JK., Ishido, S. and Jung ,JU. The collagen repeat sequence is a determinant of the degree of herpesvirus saimiri STP transforming activity. J.Virol.,74(17): 8102-8110. 2000

  • Lee, BS., Alvarez,X., Ishido, S., Lackner, AA.and Jung JU.Inhibition of intracellular transport of B cell antigen receptor complexes by Kaposi's sarcoma-associated herpesvirus K1. J Exp Med. ,192(1):11-21, 2000

  • Ishido, S., Wang, C., Lee ,BS., Cohen, GB. and Jung JU. Downregulation of major histocompatibility complex class I molecules by Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins. J Virol. ,74(11):5300-5309, 2000

  • Song, J., Nagano-Fujii, M., Wang, F., Florese R., Fujita, T., Ishido, S. and Hotta, H. Nuclear localization and intramolecular cleavage of N-terminally deleted NS5A protein of hepatitis C virus. Virus Res., 69: 109-117, 2000

  • Wang, F., Yoshida, I., Takamatsu, M., Ishido, S., Fujita, T., Oka, K. and Hotta, H. Complex formation between hepatitis C virus core protein and p21Waf1/Cip1/Sdi1. Biochem. Biophys. Res. Commun., 273(2):479-484, 2000

  • Ishido, S., Fujita, T., and Hotta, H. Possible involvement of the NS3 protein of hepatitis C virus in hepatocarcinogenesis: its interaction with the p53 tumor suppressor. In: Methods in Molecular Medicine, The Humana Press, Inc. 37-55, 2000

  • Ueyama, T., Kawashima, S., Sakoda, T., Rikitake, Y., Ishida, T., Kawai, M., Yamashita, T. , Ishido, S., Hotta, H. and Yokoyama, M. Requirement of activation of the extracellular signal-regulated kinase cascade in myocardial cell hypertrophy. J. Mol. Cell. Cardiol., 32(6):947-960, 2000

  • Rikitake, Y., Kawashima, S., Yamashita, T., Ueyama, T., Ishido, S., Hotta, H., Hirata, K. and Yokoyama, M. Lysophatidylcholine inhibits endothelial cell migration and proliferation via inhibition of the extracellular signal-regulated kinase pathway. Arterioscler. Thromb. Vasc. Biol., 20(4):1006-1012, 2000
 
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